Hydrochloric Acid → [1,3]Thiazolo[5,4-b]pyridin-2-amine

HRID 1253221노트

반응식

HRID 1253221 반응식
Cl[C:2]1[C:7]([NH2:8])=[CH:6][CH:5]=[CH:4][N:3]=1.[S-:9][C:10]#[N:11].[K+].Cl>C(O)C>[NH2:11][C:10]1[S:9][C:2]2[C:7]([N:8]=1)=[CH:6][CH:5]=[CH:4][N:3]=2

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 805282-Chloro-3-pyridylamineHCID 516872Potassium thiocyanate

생성물 1

HCID 592050[1,3]Thiazolo[5,4-b]pyridin-2-amine

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

The method described in J. Het. Chem., 14(1), 129(1977) was followed to react 2-chloro-3-aminopyridine with potassium thiocyanate and hydrochloric acid in ethanol to produce 45.3 g of 2-aminothiazolo[5,4-b]pyridine. M+Theory 151; Found 151.

출처 및 근거

ORD 기록
ord-b2a056610afd4f3081bc16b6610791e6
출처 데이터셋
uspto-grants-1988_05
특허 번호
US04748172

반응 노트

불러오는 중…