N,N'-Dimethylethylenediamine → 1-(5,6-Diphenyl-pyrazin-2-yl)-propan-1-one

HRID 12568

반응식

HRID 12568 반응식
[C:1]1([C:7]2[N:8]=[CH:9][C:10]([C:19]([O:21]C)=O)=[N:11][C:12]=2[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Al](CC)(CC)[CH2:24][CH3:25].CNCCNC>C1(C)C=CC=CC=1>[C:1]1([C:7]2[N:8]=[CH:9][C:10]([C:19](=[O:21])[CH2:24][CH3:25])=[N:11][C:12]=2[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

5

반응물 3

HCID 8070N,N'-DimethylethylenediamineHCID 16682930TriethylaluminumHCID 25033170Methyl 5,6-Diphenyl-pyrazine-2-carboxylate2회

생성물 1

HCID 112315431-(5,6-Diphenyl-pyrazin-2-yl)-propan-1-one

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

Following General Procedure O, methyl 5,6-diphenyl-pyrazine-2-carboxylate (Compound 93) (92 mg, 0.32 mmol), Et3Al (0.9 ml, 1M in hexane), DMEDA (38 mg, 0.35 mmol) in toluene was reacted to afford the title compound.

후처리

  1. customwas reacted

출처 및 근거

ORD 기록
ord-c266ff78267141f78cd7efceb38cee8f
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07728014B2

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