Hydrogen Peroxide → Tinuvin 123

HRID 1261747

반응식

HRID 1261747 반응식
[C:1]([O:25][CH:26]1[CH2:31][C:30]([CH3:33])([CH3:32])[N:29]([OH:34])[C:28]([CH3:36])([CH3:35])[CH2:27]1)(=[O:24])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]([O:12][CH:13]1[CH2:18][C:17]([CH3:20])([CH3:19])[N:16]([OH:21])[C:15]([CH3:23])([CH3:22])[CH2:14]1)=[O:11].[Cl-].[Ca+2].[Cl-].OO.C(=O)[CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH3:50].[OH-].[Na+]>C1(C)C=CC=CC=1.C(O)(=O)C>[C:1]([O:25][CH:26]1[CH2:27][C:28]([CH3:36])([CH3:35])[N:29]([O:34][CH2:50][CH2:49][CH2:48][CH2:47][CH2:46][CH2:45][CH2:44][CH3:43])[C:30]([CH3:33])([CH3:32])[CH2:31]1)(=[O:24])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]([O:12][CH:13]1[CH2:14][C:15]([CH3:22])([CH3:23])[N:16]([O:21][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])[C:17]([CH3:19])([CH3:20])[CH2:18]1)=[O:11]

참가 물질

7

반응물 5

HCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 31289NonanalHCID 5284359Calcium ChlorideHCID 11272241Bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl)decandioate

생성물 1

HCID 3592789Tinuvin 123

시약·촉매·용매 1

HCID 18331056Acetic acid toluene용매

반응 조건

온도
40 °C

실험 절차

10.0 g Bis(1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl) sebacate (Prostab 5415, commercial product of Ciba Specialty Chemicals Inc.) are dissolved in 50 ml toluene/acetic acid (1:1) and 2.5 g calcium chloride are added. 10 ml 50% aqueous hydrogen peroxide are added, followed by 20 ml nonanal and 0.2 g CuCl2. The reaction mixture is stirred for 1 h at room temperature and afterwards for 10 h at 40° C. The mixture is pure into 100 ml 0.1 N NaOH and subsequently extracted with methylene chloride. The organic phase is washed twice with water and then with sat. sodium chloride solution and dried over sodium sulfate. The organic phase is removed in vacuo and the residue subjected to column chromatography on silica gel to afford 5.5 g of product.

후처리

  1. extractionsubsequently extracted with methylene chloride
  2. washThe organic phase is washed twice with water
  3. dry with materialwith sat. sodium chloride solution and dried over sodium sulfate
  4. customThe organic phase is removed in vacuo

출처 및 근거

ORD 기록
ord-e1f9174d1f544845bdb3eca6cd0132e9
출처 데이터셋
uspto-grants-2013_06
특허 번호
US08471031B2

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