Hydrogen Bromide → HCID 12100428, 화합물

HRID 1266564노트

반응식

HRID 1266564 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[C:4]([CH3:9])[C:3]=1[CH3:10].OS(O)(=O)=O.[BrH:16].CC(N=NC(C#N)(C)C)(C#N)C.OO>ClC1C=CC=CC=1>[Br:1][C:2]1[C:3]([CH3:10])=[C:4]([C:5]([Br:8])=[CH:6][CH:7]=1)[CH2:9][Br:16]

참가 물질

7

반응물 5

HCID 260Hydrogen BromideHCID 784Hydrogen PeroxideHCID 1118Sulfuric AcidHCID 6547AzobisisobutyronitrileHCID 121004271,4-Dibromo-2,3-dimethylbenzene

생성물 1

HCID 12100428HCID 12100428, 화합물

시약·촉매·용매 1

HCID 7964Chlorobenzene용매

반응 조건

온도
70 °C

실험 절차

183.2 g (0.65 mol) of 3,6-dibromo-1,2-xylene are initially charged in 750 ml of chlorobenzene, and 2 g of conc. H2SO4 and 270.7 g (1.57 mol) of 47% strength hydrobromic acid are then added. The reaction mixture is heated to 70° C. and 0.3 g of AIBN are added. Over 14 h, 237.7 g (0.7 mol) of a 10% strength solution of hydrogen peroxide are added at 75-77° C., the mixture is stirred for another 120 min., washed 2× with 250 ml of water and once with 250 ml of saturated sodium bicarbonate solution, and the chlorobenzene is then distilled off.

후처리

  1. washwashed 2× with 250 ml of water
  2. distillationonce with 250 ml of saturated sodium bicarbonate solution, and the chlorobenzene is then distilled off

출처 및 근거

ORD 기록
ord-f8498a5b257143d5bbaaef07aa0eccd8
출처 데이터셋
uspto-grants-2003_04
특허 번호
US06548677B1

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