Dioctadecylamine → 1-(Dioctadecylamino)methyl-4-cyanobenzene

HRID 127995

반응식

HRID 127995 반응식
[CH2:1]([NH:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].Br[CH2:39][C:40]1[CH:45]=[CH:44][C:43]([C:46]#[N:47])=[CH:42][CH:41]=1>C(Cl)(Cl)Cl>[CH2:20]([N:19]([CH2:39][C:40]1[CH:45]=[CH:44][C:43]([C:46]#[N:47])=[CH:42][CH:41]=1)[CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37]

참가 물질

4

반응물 2

HCID 66989DioctadecylamineHCID 869964-(Bromomethyl)benzonitrile

생성물 1

HCID 204329871-(Dioctadecylamino)methyl-4-cyanobenzene수율 97.5%

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

Dioctadecylamine (26.0 g., 0.05 M), α-bromo-p-tolunitrile (4.9 g., 0.025 M) and chloroform (500 ml.) are stirred at room temperature for 24 hours. The precipitate of dioctadecylamine hydrobromide is filtered off and the filtrate concentrated under reduced pressure. The residue is slurried in methanol, filtered, and evaporated to give 1-(dioctadecylamino)methyl-4-cyanobenzene (15.5 g., 97.5% yield).

후처리

  1. filtrationThe precipitate of dioctadecylamine hydrobromide is filtered off
  2. concentrationthe filtrate concentrated under reduced pressure
  3. filtrationfiltered
  4. customevaporated

출처 및 근거

ORD 기록
ord-5ed02cd3ec794e669594e5566a0b3dfc
출처 데이터셋
uspto-grants-1981_03
특허 번호
US04258061

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