Hydrazine hydrate (1:1) → HCID 178489133, 화합물

HRID 1294905노트

반응식

HRID 1294905 반응식
F[C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]([C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=1)=O.O.[NH2:20][NH2:21]>CN(C1C=CN=CC=1)C>[CH3:18][O:17][C:14]1[CH:15]=[CH:16][C:11]([C:9]2[C:3]3[C:2](=[C:7]([CH3:8])[CH:6]=[CH:5][CH:4]=3)[NH:21][N:20]=2)=[CH:12][CH:13]=1

참가 물질

4

반응물 2

HCID 24654Hydrazine hydrate (1:1)HCID 67021114(2-Fluoro-3-methylphenyl)(4-methoxyphenyl)methanone

생성물 1

HCID 178489133HCID 178489133, 화합물수율 48.5%

시약·촉매·용매 1

HCID 142844-(Dimethylamino)pyridine촉매

실험 절차

Prepared according to Method D Step A from (2-Fluoro-3-methylphenyl)-(4-methoxyphenyl)-methanone (3.6 g, 14.7 mmol), hydrazine hydrate (4.3 mL, 140 mmol) and DMAP (1.8 g, 14.7 mmol) to give the product (1.7 g) as a yellow solid.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-ae539fed791e49d99130f2290db09c74
출처 데이터셋
uspto-grants-2007_07
특허 번호
US07241791B2

반응 노트

불러오는 중…