Hydrogen Bromide → Hydrochloric Acid

HRID 1350593

반응식

HRID 1350593 반응식
C[O:2][C:3](=[O:13])[CH2:4][CH2:5][N:6]([CH3:12])[CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].Br.[ClH:15]>O>[CH3:12][N:6]([CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[CH2:5][CH2:4][C:3]([OH:13])=[O:2].[ClH:15]

참가 물질

6

반응물 3

HCID 260Hydrogen BromideHCID 313Hydrochloric Acid2회HCID 16726422Methyl 3-(methyl(pentyl)amino)propanoate

생성물 2

HCID 313Hydrochloric AcidHCID 16036977N-Methyl-N-pentyl-beta-alanine

시약·촉매·용매 1

HCID 962Water용매

실험 절차

The hydrolysis can be performed by refluxing the N-methyl-N-pentyl-β-alanine methyl ester in a diluted mineral acid, but can also be performed by refluxing in water at least until no ester can be detected any further. Formation of the hydrohalogenide such as the hydrobromide or the hydrochloride, preferably of the hydrochloride (X═Cl) can be effected by addition of an aqueous solution of the appropriate mineral acid. The resulting N-methyl-N-pentyl-β-alanine hydrohalogenide, e.g., hydrochloride, can be isolated by distilling of the water and by a crystallization of the residue in a suitable solvent such as toluene/acetone or methyl ethyl ketone, preferably in methyl ethyl ketone.

후처리

  1. customThe hydrolysis

출처 및 근거

ORD 기록
ord-1d5cd8d4169b425f90d0708b8e0c21f8
출처 데이터셋
uspto-grants-2007_05
특허 번호
US07214818B2

연결된 노트

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