N-bromobutanimide → 3-(Bromomethyl)phenyl acetate

HRID 1351087노트

반응식

HRID 1351087 반응식
[C:1]([O:4][C:5]1[CH:6]=[C:7]([CH3:11])[CH:8]=[CH:9][CH:10]=1)(=[O:3])[CH3:2].[Br:12]N1C(=O)CCC1=O>ClC(Cl)(Cl)Cl.N(C(C)(C)C#N)=NC(C)(C)C#N>[C:1]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH2:11][Br:12])[CH:6]=1)(=[O:3])[CH3:2]

참가 물질

5

반응물 2

HCID 67184N-bromobutanimideHCID 67406Cresatin

생성물 1

HCID 64220753-(Bromomethyl)phenyl acetate수율 100.4%

시약·촉매·용매 2

HCID 6547Azobisisobutyronitrile촉매HCID 5943Carbon Tetrachloride용매

실험 절차

A suspension of m-tolyl acetate (583 mg), N-bromosuccinimide (691 mg) and α,α′-azobis(isobutyronitrile) (13 mg) in tetrachloromethane (10 mL) was refluxed for 1 hour. The reaction mixture was cooled to room temperature, and the insoluble material was removed by filtration. The filtrate was concentrated to give the title compound (893 mg).

후처리

  1. temperaturewas refluxed for 1 hour
  2. customthe insoluble material was removed by filtration
  3. concentrationThe filtrate was concentrated

출처 및 근거

ORD 기록
ord-d803bf4dc0984eeba3872c4297924e16
출처 데이터셋
uspto-grants-2007_05
특허 번호
US07217697B2

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