2,1,3-Benzothiadiazol-5-ylmethanol → 2,1,3-Benzothiadiazole-5-carbaldehyde

HRID 1357750

반응식

HRID 1357750 반응식
[OH:1][CH2:2][C:3]1[CH:11]=[CH:10][C:6]2=[N:7][S:8][N:9]=[C:5]2[CH:4]=1>C(Cl)(Cl)Cl.[O-2].[O-2].[Mn+4]>[N:7]1[S:8][N:9]=[C:5]2[CH:4]=[C:3]([CH:2]=[O:1])[CH:11]=[CH:10][C:6]=12

참가 물질

4

반응물 1

HCID 27762942,1,3-Benzothiadiazol-5-ylmethanol

생성물 1

HCID 27762902,1,3-Benzothiadiazole-5-carbaldehyde수율 72.3%

시약·촉매·용매 2

HCID 178418406HCID 178418406, 화합물촉매HCID 6212Chloroform용매

실험 절차

5-Hydroxymethylbenzo-2, 1,3-thiadiazole (2.6 g, 16 mmol) and manganese dioxide (6.0 g, 64 mmol) in chloroform (150 mL) were stirred at room temperature overnight. The reaction mixture was filtered off and the filtrate was evaporated to provide 1.9 g of the title compound.

후처리

  1. filtrationThe reaction mixture was filtered off
  2. customthe filtrate was evaporated

출처 및 근거

ORD 기록
ord-d6214540b07f41f691e40f83b9cf0f40
출처 데이터셋
uspto-grants-2003_07
특허 번호
US06593335B1

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