Methyl Isocyanate → n-[(5-{6-[((3r)Oxolan-3-yl)amino]purin-9-yl}(3s,2r,4r,5r)-3,4-dihydroxyoxolan-2-yl)methyl](propylamino)carboxamide
반응식
[O:1]1[CH2:5][CH2:4][C@@H:3]([NH:6][C:7]2[N:15]=[CH:14][N:13]=[C:12]3[C:8]=2[N:9]=[CH:10][N:11]3[C@@H:16]2[O:20][C@H:19]([CH2:21][NH:22][C:23]([NH:25][CH3:26])=[O:24])[C@@H:18]([OH:27])[C@H:17]2[OH:28])[CH2:2]1.[CH2:29](N=C=O)[CH2:30]C.CN=C=O>>[O:1]1[CH2:5][CH2:4][C@@H:3]([NH:6][C:7]2[N:15]=[CH:14][N:13]=[C:12]3[C:8]=2[N:9]=[CH:10][N:11]3[C@@H:16]2[O:20][C@H:19]([CH2:21][NH:22][C:23]([NH:25][CH2:26][CH2:29][CH3:30])=[O:24])[C@@H:18]([OH:27])[C@H:17]2[OH:28])[CH2:2]1참가 물질
4
반응물 3
생성물 1
실험 절차
Compound 93 was prepared in the manner of compound 24 substituting propyl isocyanate for methyl isocyanate and refluxing for 16 h [MS 422.3 (M+1)].