Triethylamine → 2-Ethyl-2-methacryloyloxyadamantane

HRID 1369358

반응식

HRID 1369358 반응식
[CH2:1]([C:3]1([OH:13])[CH:10]2[CH2:11][CH:6]3[CH2:7][CH:8]([CH2:12][CH:4]1[CH2:5]3)[CH2:9]2)[CH3:2].C(N(CC)CC)C.[C:21](Cl)(=[O:25])[C:22]([CH3:24])=[CH2:23]>CC(CC(C)C)=O>[C:21]([O:13][C:3]1([CH2:1][CH3:2])[CH:4]2[CH2:12][CH:8]3[CH2:7][CH:6]([CH2:11][CH:10]1[CH2:9]3)[CH2:5]2)(=[O:25])[C:22]([CH3:24])=[CH2:23]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 13528Methacryloyl chlorideHCID 44019512-Ethyl-2-adamantanol

생성물 1

HCID 98136452-Ethyl-2-methacryloyloxyadamantane수율 60%

시약·촉매·용매 1

HCID 7909Methyl Isobutyl Ketone용매

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온도
90 °C

실험 절차

180 g of 2-Ethyl-2-adamantanol, 303 g of triethylamine and 500 g of methylisobutyl ketone were mixed by stirring at 90° C. While stirring, 157 g of methacrylic acid chloride was added dropwise to the mixture. After completion of the dropwise addition, the mixture was further stirred for 72 hours. Then, extraction and distillation were conducted to obtain 2-ethyl-2-adamantyl methacrylate at the yield of 60%.

후처리

  1. stirringWhile stirring
  2. additionAfter completion of the dropwise addition
  3. stirringthe mixture was further stirred for 72 hours
  4. extractionThen, extraction and distillation

출처 및 근거

ORD 기록
ord-9a8617f7ceab4cba9d7d1e46a274944a
출처 데이터셋
uspto-grants-2003_06
특허 번호
US06579659B2

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