1-Butanol → n-Butylphosphorodichloridate

HRID 1375287노트

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HRID 1375287 반응식
[CH2:1]([OH:5])[CH2:2][CH2:3][CH3:4].[O:6]=[P:7](Cl)([Cl:9])[Cl:8]>C(Cl)Cl>[P:7]([Cl:9])([Cl:8])([O:5][CH2:1][CH2:2][CH2:3][CH3:4])=[O:6]

참가 물질

4

반응물 2

HCID 2631-ButanolHCID 24813Phosphorus oxychloride

생성물 1

HCID 137039n-Butylphosphorodichloridate

시약·촉매·용매 1

HCID 6344Dichloromethane용매

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온도
0 °C

실험 절차

To a solution of butanol (0.98 mL, 10.0 mmol) in anhydrous CH2Cl2 (10 mL) was added dropwise POCl3 (3.0 mL, 32.0 mmol) at 0° C. After stirring at 0° C. for 1 h, the mixture was refluxed for 5 h and then followed by vacuum distillation to afford butyl dichlorophosphate.

후처리

  1. temperaturethe mixture was refluxed for 5 h
  2. distillationfollowed by vacuum distillation

출처 및 근거

ORD 기록
ord-741ee96edd9246e7866739cadb9e39d0
출처 데이터셋
uspto-grants-2007_01
특허 번호
US07166744B2

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