Nitromethane → Benzenepropanoic acid, b-(nitromethyl)-, methyl ester
반응식
[CH3:1][O:2][C:3](=[O:12])[CH:4]=[CH:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[N+:13]([CH3:16])([O-:15])=[O:14].CN(C)C(=N)N(C)C>C(OCC)C.Cl>[CH3:1][O:2][C:3](=[O:12])[CH2:4][CH:5]([C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=1)[CH2:16][N+:13]([O-:15])=[O:14]참가 물질
6
실험 절차
A mixture of 300 g of cinnamic acid methyl ester, 500 g of nitromethane and 39 g of tetramethylguanidine is allowed to stir at room temperature for 72 hours. The solution is diluted with diethyl ether and aqueous hydrochloric acid solution (1 N, 1 liter) is added. The organic layer is separated, dried over anhydrous magnesium sulfate, and evaporated to give 4-nitro-3-phenylbutanoic acid methyl ester.
후처리
- additionis added
- customThe organic layer is separated
- dry with materialdried over anhydrous magnesium sulfate
- customevaporated
출처 및 근거
- ORD 기록
- ord-8047cb0e83d14c57a0028cc1464f6079
- 출처 데이터셋
- uspto-grants-1986_04
- 특허 번호
- US04584313
반응 노트
불러오는 중…