Potassium Iodide → Hydrochloric Acid

HRID 1382413

반응식

HRID 1382413 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]2)=[CH:4][CH:3]=1.[Cl:14][CH2:15][CH2:16][CH:17]([OH:28])[CH2:18][O:19][C:20]1[CH:25]=[CH:24][C:23]([Cl:26])=[C:22]([CH3:27])[CH:21]=1.C(=O)([O-])[O-].[Na+].[Na+].[I-].[K+]>CC(O)C.C(O)CCC>[Cl:26][C:23]1[CH:24]=[CH:25][C:20]([O:19][CH2:18][CH:17]([OH:28])[CH2:16][CH2:15][N:11]2[CH2:12][CH2:13][N:8]([C:5]3[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=3)[CH2:9][CH2:10]2)=[CH:21][C:22]=1[CH3:27].[ClH:14]

참가 물질

8

반응물 4

HCID 4875Potassium IodideHCID 10340Sodium CarbonateHCID 752601-(4-Fluorophenyl)piperazineHCID 133239084-Chloro-1-(4-chloro-3-methylphenoxy)-2-butanol

생성물 2

HCID 313Hydrochloric AcidHCID 14422854HCID 14422854, 화합물

시약·촉매·용매 2

HCID 2631-Butanol용매HCID 3776Isopropanol용매

실험 절차

This compound was prepared according to the procedure of Example 97. A mixture of 1.8 g (0.01 mole) of 1-(4-fluorophenyl)piperazine, 2.5 g (0.01 mole) of 4-chloro-1-(4-chloro-3-methylphenoxy)-2-butanol, 5.2 g (0.05 mole) of anhydrous sodium carbonate and 0.1 g of potassium iodide in a total volume of 200 ml of 1-butanol gave a golden oil as residue. The hydrochloride was formed in 2-propanol saturated with hydrogen chloride and the collected solid was recrystallized from methanol-water-ethyl ether to give 1.7 g (36%) of white solid, m.p. 199°-203° C.

후처리

  1. customThis compound was prepared
  2. customgave a golden oil as residue

출처 및 근거

ORD 기록
ord-bfbc08663b554189a380d68bbfdcde06
출처 데이터셋
uspto-grants-1989_02
특허 번호
US04806555

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