Benzoyl chloride → 3-Benzoyloxy-5-methylisoxazole

HRID 1390042

반응식

HRID 1390042 반응식
[OH:1][C:2]1[CH:6]=[C:5]([CH3:7])[O:4][N:3]=1.[C:8](Cl)(=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>C(N(CC)CC)C>[C:8]([O:1][C:2]1[CH:6]=[C:5]([CH3:7])[O:4][N:3]=1)(=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

참가 물질

4

반응물 2

HCID 7412Benzoyl chlorideHCID 24781Hymexazol

생성물 1

HCID 124150073-Benzoyloxy-5-methylisoxazole

시약·촉매·용매 1

HCID 8471Triethylamine용매

실험 절차

3-Hydroxy-5-methylisoxazole was reacted with benzoyl chloride in the presence of triethylamine to give 3-benzoyloxy-5-methylisoxazole, which was then reacted with N-bromosuccinimide, to give 3-benzoyloxy-5-bromomethylisoxazole. This was reacted with disodium thioglycolate to give 3-hydroxyisoxazol-5-ylmethylthioacetic acid, which was treated with diphenyldiazomethane to give the benzhydryl ester.

출처 및 근거

ORD 기록
ord-784b205c021847b0b97909951156c164
출처 데이터셋
uspto-grants-1981_01
특허 번호
US04247548

연결된 노트

불러오는 중…