Sodium borohydride → 1,5-Di-(3,3-dimethylnorborn-2-yl)-3-pentanol

HRID 1390551

반응식

HRID 1390551 반응식
[CH3:1][C:2]1([CH3:24])[CH:7]2[CH2:8][CH:4]([CH2:5][CH2:6]2)[CH:3]1[CH2:9][CH2:10][C:11](=[O:23])[CH2:12][CH2:13][CH:14]1[C:19]([CH3:21])([CH3:20])[CH:18]2[CH2:22][CH:15]1[CH2:16][CH2:17]2.[BH4-].[Na+]>C(O)C>[CH3:1][C:2]1([CH3:24])[CH:7]2[CH2:8][CH:4]([CH2:5][CH2:6]2)[CH:3]1[CH2:9][CH2:10][CH:11]([OH:23])[CH2:12][CH2:13][CH:14]1[C:19]([CH3:20])([CH3:21])[CH:18]2[CH2:22][CH:15]1[CH2:16][CH2:17]2

참가 물질

4

반응물 2

HCID 4311764Sodium borohydrideHCID 213328461,5-Di-(3,3-dimethylnorborn-2-yl)-3-pentanone

생성물 1

HCID 213328421,5-Di-(3,3-dimethylnorborn-2-yl)-3-pentanol

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

The ketone, 1,5-di-(3,3-dimethylnorborn-2-yl)-3-pentanone (2 grams) was dissolved in 100 ml. of ethanol and stirred with 2 grams of sodium borohydride overnight. The solvent was removed in vacuo and the residue partitioned between ethyl ether and water. The organic layer was dried over sodium sulfate. After filtration, and removal of solvent a colorless oil was obtained that crystallized on standing, m.p. 55° C.-56° C.

후처리

  1. customThe solvent was removed in vacuo
  2. customthe residue partitioned between ethyl ether and water
  3. dry with materialThe organic layer was dried over sodium sulfate
  4. filtrationAfter filtration, and removal of solvent a colorless oil
  5. customwas obtained
  6. customthat crystallized

출처 및 근거

ORD 기록
ord-8e660559ec5a4d1a89cdbf6e555f403d
출처 데이터셋
uspto-grants-1979_02
특허 번호
US04139559

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