Benzophenone → 2-Propenoic acid, 4-benzoylphenyl ester

HRID 1413920노트

반응식

HRID 1413920 반응식
[OH:1][C:2]1[CH:15]=[CH:14][C:5]([C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:7])=[CH:4][CH:3]=1.[OH-].[Na+].[C:18](C1C=CC=CC=1)(=[O:25])[C:19]1C=CC=C[CH:20]=1.C(Cl)(=O)C=C>O>[C:18]([O:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:7])=[CH:14][CH:15]=1)(=[O:25])[CH:19]=[CH2:20]

참가 물질

6

반응물 4

HCID 3102BenzophenoneHCID 13140Acryloyl chlorideHCID 143474-HydroxybenzophenoneHCID 14798Sodium Hydroxide

생성물 1

HCID 30151312-Propenoic acid, 4-benzoylphenyl ester

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A 100 g quantity of 4-hydroxybenzophenone was added to 500 ml of water containing 22.0 g of sodium hydroxide. The solution was stirred until all of the benzophenone had dissolved. After the solution had cooled to 5°-10° C., there was added 45.5 g of acrylyl chloride over a period of 30 minutes, to yield a white solid which was recovered by filtration after the solution had been stirred for 2 hours at 5°-10° C. and an additional hour at room temperature. The white solid was recrystallized from ethanol and found to have m.p. 44°-46° C. Infrared and NMR spectra confirmed the structure of 4-acryloxybenzophenone.

후처리

  1. dissolutionhad dissolved
  2. temperatureAfter the solution had cooled to 5°-10° C.
  3. customto yield a white solid which
  4. filtrationwas recovered by filtration after the solution
  5. customThe white solid was recrystallized from ethanol

출처 및 근거

ORD 기록
ord-92a55364cb254fa58642eb563815bfa4
출처 데이터셋
uspto-grants-1981_02
특허 번호
US04251618

반응 노트

불러오는 중…