Pyridine → 2-methoxy-N,N-dimethyl-2-(2-pyridyl)thioacetamide
반응식
P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:2].[CH3:15][O:16][CH:17]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][N:24]=1)[C:18]([N:20]([CH3:22])[CH3:21])=O.N1C=CC=CC=1.[OH-].[Na+]>O>[CH3:15][O:16][CH:17]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][N:24]=1)[C:18]([N:20]([CH3:22])[CH3:21])=[S:2]참가 물질
6
실험 절차
Phosphorus pentasulfide (4 g.) is added to 9.7 g. of 2-methoxy-N,N-dimethyl-2-(2-pyridyl)acetamide in 25 ml. of pyridine. The mixture is heated on a steam bath for two hours, then 250 ml. of water and 10 ml. of 5% aqueous sodium hydroxide solution are added. The mixture is extracted with chloroform and the extracts are dried and concentrated and the residue is recrystallized to give 2-methoxy-N,N-dimethyl-2-(2-pyridyl)thioacetamide.
후처리
- temperatureThe mixture is heated on a steam bath for two hours
- extractionThe mixture is extracted with chloroform
- customthe extracts are dried
- concentrationconcentrated
- customthe residue is recrystallized
출처 및 근거
- ORD 기록
- ord-d2fd9e6ce9664b8bbbe1c95b6a92f624
- 출처 데이터셋
- uspto-grants-1977_01
- 특허 번호
- US04001241
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