Dimethyl Sulfoxide → 3-tert-butoxycarbonyl-7-chloro-6-(4-cyanobenzyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine

HRID 141792노트

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][c:11]2[c:12]([c:15]([OH:20])[c:16]([Cl:19])[cH:17][cH:18]2)[CH2:13][CH2:14]1.[C:21](=[O:22])([O-:23])[O-:24].[C:27](#[N:28])[c:29]1[cH:30][cH:31][c:32]([CH2:33][Br:34])[cH:35][cH:36]1.[CH3:37][S:38]([CH3:39])=[O:40].[K+:25].[K+:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][c:11]2[c:12]([c:15]([O:20][CH2:33][c:32]3[cH:31][cH:30][c:29]([C:27]#[N:28])[cH:36][cH:35]3)[c:16]([Cl:19])[cH:17][cH:18]2)[CH2:13][CH2:14]1