Water → 3-(Benzyloxy)-4-methoxybenzyl alcohol

HRID 1420775

반응식

HRID 1420775 반응식
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][C:16]=1[O:17][CH3:18])[CH:12]=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[BH4-].[Na+].O>CO.CCOCC>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH2:12][OH:13])[CH:14]=[CH:15][C:16]=1[O:17][CH3:18])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

6

반응물 3

HCID 962WaterHCID 806713-Benzyloxy-4-methoxybenzaldehydeHCID 4311764Sodium borohydride

생성물 1

HCID 746223-(Benzyloxy)-4-methoxybenzyl alcohol

시약·촉매·용매 2

HCID 887Methanol용매HCID 3283Diethyl Ether용매

실험 절차

A solution of 0.35 mol of the compound obtained in Step 1 in 400 ml of methanol and 1.5 equivalents of sodium borohydride is stirred for 6 hours at ambient temperature and then 500 ml of acidified water are slowly added. The precipitate obtained is taken up in ether; the organic phase is subsequently extracted, dried, filtered and then evaporated off under reduced pressure, allowing the expected product to be isolated.

후처리

  1. customThe precipitate obtained
  2. extractionthe organic phase is subsequently extracted
  3. customdried
  4. filtrationfiltered
  5. customevaporated off under reduced pressure
  6. customto be isolated

출처 및 근거

ORD 기록
ord-fc144128b9d74547bc6aca0d6074e7de
출처 데이터셋
uspto-grants-2000_06
특허 번호
US06071945

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