Hydrochloric Acid → HCID 91658617, 화합물

HRID 1436376

반응식

HRID 1436376 반응식
[ClH:1].[CH2:2]([O:4][C:5]([C:7]1([NH:10]C(OC(C)(C)C)=O)[CH2:9][CH2:8]1)=[O:6])[CH3:3]>C(OCC)(=O)C>[Cl-:1].[CH2:2]([O:4][C:5]([C:7]1([NH3+:10])[CH2:9][CH2:8]1)=[O:6])[CH3:3]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 10242916Ethyl 1-((tert-butoxycarbonyl)amino)cyclopropanecarboxylate

생성물 1

HCID 91658617HCID 91658617, 화합물

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매2회

실험 절차

A saturated solution of HCl in ethyl acetate (20 mL) was added under nitrogen to a solution of 1-[[(1,1-dimethylethoxy)carbonyl]amino]cyclopropane carboxylic acid ethyl ester (10.07 g, 43.9 mmol), prepared in the previous step, in 20 mL of ethyl acetate at room temperature. After the addition, the reaction was stirred at room temperature for 1 h. The solid present was collected by filtration, rinsed with ethyl acetate and dried under reduced pressure to give 1-ethoxycarbonyl-cyclopropyl-ammonium chloride as a white solid.

후처리

  1. additionAfter the addition
  2. filtrationThe solid present was collected by filtration
  3. washrinsed with ethyl acetate
  4. customdried under reduced pressure

출처 및 근거

ORD 기록
ord-147f78c6847047b6a58b7ae09f3f9b92
출처 데이터셋
uspto-grants-2009_11
특허 번호
US07618990B2

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