반응식
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[S:9]([N:12]([C:22]1[C:27]([O:28][CH3:29])=[N:26][C:25](Cl)=[CH:24][N:23]=1)COCCO[Si](C)(C)C)(=[O:11])=[O:10].[C:31]([NH2:35])(=[O:34])[CH2:32][OH:33].[H-].[Na+]>CN(C)C=O>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[S:9]([NH:12][C:22]1[N:23]=[CH:24][C:25]([NH:35][C:31](=[O:34])[CH2:32][OH:33])=[N:26][C:27]=1[O:28][CH3:29])(=[O:10])=[O:11]참가 물질
5
반응물 3
생성물 1
시약·촉매·용매 1
실험 절차
Procedure as for Example 115 using 2,3-dichloro-N-(5-chloro-3-methoxy-2-pyrazinyl)-N-({2-[(trimethylsilyl)oxy]ethoxy}methyl)benzenesulphonamide (Example 115a) (0.25 g), glycolamide (0.066 g) and sodium hydride (0.035 g of a 60% dispersion in oil) in N,N-dimethylformamide (5 mL). Yield 0.075 g.
출처 및 근거
- ORD 기록
- ord-faa5e6a36b584441ac2f4a5d723c053b
- 출처 데이터셋
- uspto-grants-2010_02
- 특허 번호
- US07662825B2
연결된 노트
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