M-Cresol → HCID 178484374, 화합물

HRID 1464056

반응식

HRID 1464056 반응식
Cl.[NH2:2][C:3]1[CH:8]=[CH:7][C:6]([F:9])=[CH:5][C:4]=1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[CH3:16][N:17]([CH3:20])[C:18]#[N:19].C1C(O)=CC=CC=1C>>[F:9][C:6]1[CH:7]=[CH:8][C:3]([NH:2][C:18]([N:17]([CH3:20])[CH3:16])=[NH:19])=[C:4]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:5]=1

참가 물질

4

반응물 3

HCID 342M-CresolHCID 15112DimethylcyanamideHCID 190892185-Fluoro-[1,1'-biphenyl]-2-amine hydrochloride

생성물 1

HCID 178484374HCID 178484374, 화합물

실험 절차

A mixture of 2-amino-5-fluorobiphenyl hydrochloride (3.6 g), N,N-dimethylcyanamide (1.68 g) and m-cresol (25 ml) was heated at 90°-95° C. for 8 hours to give N-(5-fluoro-2-biphenylyl)-N',N'-dimethylguanidine (m.p. 160°-161° C.) which was recrystallised from hexane.

후처리

  1. temperaturewas heated at 90°-95° C. for 8 hours

출처 및 근거

ORD 기록
ord-20fb8c4e79754dc3a355821d79cc8c76
출처 데이터셋
uspto-grants-1994_04
특허 번호
US05302720

연결된 노트

불러오는 중…