Hydrochloric Acid → N-[[(3,4-dichlorophenyl)amino]carbonyl]-2-thiophenesulfonamide

HRID 1464133

반응식

HRID 1464133 반응식
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[S:6]([NH2:9])(=[O:8])=[O:7].[Cl:10][C:11]1[CH:12]=[C:13]([N:18]=[C:19]=[O:20])[CH:14]=[CH:15][C:16]=1[Cl:17].[OH-].[Na+].Cl>CC(C)=O>[Cl:10][C:11]1[CH:12]=[C:13]([NH:18][C:19]([NH:9][S:6]([C:2]2[S:1][CH:5]=[CH:4][CH:3]=2)(=[O:8])=[O:7])=[O:20])[CH:14]=[CH:15][C:16]=1[Cl:17]

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 76073,4-Dichlorophenyl isocyanateHCID 14798Sodium HydroxideHCID 728812-Thiophenesulfonamide

생성물 1

HCID 19089331N-[[(3,4-dichlorophenyl)amino]carbonyl]-2-thiophenesulfonamide수율 39%

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

2-Thiophenesulfonamide (1.55 g, 9.5 mmole) was combined with 3,4-dichlorophenyl isocyanate (1.79 g, 9.5 mmole), 1N NaOH (9.5 ml) and acetone (25 ml) followed by 1N HCl (9.5 ml) using the method of Example 4B to give the named product (1.3 g).

출처 및 근거

ORD 기록
ord-2290d93fc6d44ee9b84ed19eacd6d4ea
출처 데이터셋
uspto-grants-1994_04
특허 번호
US05302724

연결된 노트

불러오는 중…