반응식
[Cl:1][C:2]1[C:6]([CH3:7])=[CH:5][N:4]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)[N:3]=1.[Mn]([O-])(=O)(=O)=[O:15].[Na+].[OH2:20]>C(O)(C)(C)C>[Cl:1][C:2]1[C:6]([C:7]([OH:15])=[O:20])=[CH:5][N:4]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)[N:3]=1참가 물질
5
반응 조건
- 온도
- 80 °C
실험 절차
In another embodiment, 3-(3-chloro-4-methyl-1H-pyrazol-1-yl)pyridine (3) is further oxidized by sodium permanganate in water and tert-butanol and heated at about 80° C. The 3-chloro-1-(pyridin-3-yl)-1H-pyrazole-4-carboxylic acid (4) can be isolated and purified by standard techniques.
출처 및 근거
- ORD 기록
- ord-1656679b83cf477bb4a6ee673c9b7466
- 출처 데이터셋
- uspto-grants-2016_08
- 특허 번호
- US09422265B2
연결된 노트
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