Benzylamine → Pentan-2-YL 4-hydroxybenzoate
반응식
C([O:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]([O:13][CH:14]([CH3:18])[CH2:15][CH2:16][CH3:17])=[O:12])=[CH:7][CH:6]=1)(=O)C.C(N)C1C=CC=CC=1>C(O)C.C(Cl)(Cl)Cl>[OH:4][C:5]1[CH:6]=[CH:7][C:8]([C:11]([O:13][CH:14]([CH3:18])[CH2:15][CH2:16][CH3:17])=[O:12])=[CH:9][CH:10]=1참가 물질
5
실험 절차
Two grams of the crude compound (2) was dissolved in 50 ml of ethanol and 4 g of benzylamine was added dropwise. The mixture was stirred at room temperature for 4 hours, then diluted with 500 ml of chloroform, washed with dilute hydrochloric acid and water in this order, and dried with magnesium sulfate. After the solvent was evaporated, the residue was subjected to isolation and purification by silica gel column chromatography to obtain 1.6 g of a final compound.
후처리
- washwashed with dilute hydrochloric acid and water in this order
- dry with materialdried with magnesium sulfate
- customAfter the solvent was evaporated
- customthe residue was subjected to isolation and purification by silica gel column chromatography
출처 및 근거
- ORD 기록
- ord-1d632962eec24eb9be4f8d0db8c50c8f
- 출처 데이터셋
- uspto-grants-1994_12
- 특허 번호
- US05374375
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