Hydrochloric Acid → HCID 5312382, 화합물

HRID 1497005노트

반응식

HRID 1497005 반응식
[C:1]([O:14]CC)(=[O:13])/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[OH-].[Na+].Cl>CO>[C:1]([OH:14])(=[O:13])/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 12387502HCID 12387502, 화합물

생성물 1

HCID 5312382HCID 5312382, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

반응 조건

온도
60 °C

실험 절차

Ethyl (2E,4E)-dodeca-2,4-dienoate (11.84 g) was dissolved in methanol (130 ml) and 2M aqueous sodium hydroxide solution (35 ml) was added. The reaction mixture was heated to 60° C. until full conversion was observed. After cooling down to room temperature the mixture was acidified with diluted aqueous HCl. The reaction mixture was extracted with ethyl acetate and the organic layer was washed with brine, dried over sodium sulfate, and solvents were evaporated. The crude product was used for the next step without further purification.

후처리

  1. temperatureAfter cooling down to room temperature the mixture
  2. extractionThe reaction mixture was extracted with ethyl acetate
  3. washthe organic layer was washed with brine
  4. dry with materialdried over sodium sulfate, and solvents
  5. customwere evaporated
  6. customThe crude product was used for the next step without further purification

출처 및 근거

ORD 기록
ord-bf8a9aca678d4fdf98bbda2e9d67e899
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09199948B2

반응 노트

불러오는 중…