Sodium Hydroxide → HCID 178510736, 화합물
반응식
[OH-:1].[Na+].Cl.[NH2:4]O.[C:6]1([C:12]2([CH2:17][C:18]#[N:19])[O:16][CH2:15][CH2:14][O:13]2)[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>CO>[OH:1][NH:19][C:18](=[NH:4])[CH2:17][C:12]1([C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=2)[O:16][CH2:15][CH2:14][O:13]1참가 물질
5
실험 절차
NaOH (3.1 g, 77 mmol) is added to hydroxylamine hydrochloride (5.2 g, 75 mmol) at 0° C. and is stirred for 15 min. A solution of (2-phenyl-1,3-dioxolan-2-yl)acetonitrile (7 g, 37 mmol) in methanol (25 mL) is added dropwise to the reaction mixture at 0° C. The reaction mixture is allowed to warm to room temperature and is heated at 90° C. for 16 h. The solvent was evaporated under reduced pressure to afford the title compound as a brown solid (7 g, 85%) which is used in the next step without purification.
후처리
- temperatureis heated at 90° C. for 16 h
- customThe solvent was evaporated under reduced pressure
출처 및 근거
- ORD 기록
- ord-e9626a55b09b48bcbad4e2421b852a07
- 출처 데이터셋
- uspto-grants-2015_07
- 특허 번호
- US09073926B2
반응 노트
불러오는 중…