Acetone → 1-Allyloxycarbonyl-2-amino-4,5-dicyanoimidazole

HRID 1576951노트

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HRID 1576951 반응식
[NH2:1][C:2]1[NH:3][C:4]([C:9]#[N:10])=[C:5]([C:7]#[N:8])[N:6]=1.Cl[C:12]([O:14][CH2:15][CH:16]=[CH2:17])=[O:13].CC(C)=O.[OH-].[Na+]>O>[CH2:15]([O:14][C:12]([N:3]1[C:4]([C:9]#[N:10])=[C:5]([C:7]#[N:8])[N:6]=[C:2]1[NH2:1])=[O:13])[CH:16]=[CH2:17]

참가 물질

6

반응물 4

HCID 180AcetoneHCID 14798Sodium HydroxideHCID 18052Allyl chloroformateHCID 1704461H-Imidazole-4,5-dicarbonitrile, 2-amino-

생성물 1

HCID 215104281-Allyloxycarbonyl-2-amino-4,5-dicyanoimidazole

시약·촉매·용매 1

HCID 962Water용매

실험 절차

2 g of 2-amino-4,5-dicyanoimidazole and 2 g of allyl chloroformate were added to 20 ml of acetone and further 3 ml of water solution containing 20% of sodium hydroxide was added dropwise to it under stirring at a temperature of 15° to 20°C. After the resulting solution was stirred during an hour at a room temperature, it was poured into ice-water and thereby white crystal was separated out.

후처리

  1. additionwas added dropwise to it
  2. stirringAfter the resulting solution was stirred during an hour at a room temperature
  3. customwhite crystal was separated out

출처 및 근거

ORD 기록
ord-4693d9867d6c469b84c78e77938f2f51
출처 데이터셋
uspto-grants-1976_09
특허 번호
US03983241

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