2-Methylimidazole → 1-((6-chloro-1,3-benzodioxol-5-yl)methyl)2-methyl-1H-imidazole
반응식
[CH3:1][C:2]1[NH:3][CH:4]=[CH:5][N:6]=1.[H-].[Na+].[CH2:9]1[O:13][C:12]2[CH:14]=[C:15]([Cl:20])[C:16]([CH2:18]Cl)=[CH:17][C:11]=2[O:10]1>CN(C)C=O>[Cl:20][C:15]1[C:16]([CH2:18][N:3]2[CH:4]=[CH:5][N:6]=[C:2]2[CH3:1])=[CH:17][C:11]2[O:10][CH2:9][O:13][C:12]=2[CH:14]=1참가 물질
5
실험 절차
The operation is carried out as in Stage 1 of Example 11 starting with 12.3 g of 2-methyl-1H-imidazole, 7.92 g of sodium hydride with 50% oil, 150 ml of N dimethylformamide and 33.8 g of 6-chloropiperonyl chloride.
출처 및 근거
- ORD 기록
- ord-6b398965cfb84cc889a194adca6f3e3c
- 출처 데이터셋
- uspto-grants-1999_08
- 특허 번호
- US05932741
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