Benzyl Chloride → HCID 907980, 화합물

HRID 1605176노트

반응식

HRID 1605176 반응식
[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:19])[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[C:8]([CH3:12])[O:9]2)=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+].[K].[CH2:27](Cl)[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>CC(C)=O>[CH2:27]([O:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:19])[C:7]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[C:8]([CH3:12])[O:9]2)=[CH:4][CH:3]=1)[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1

참가 물질

6

반응물 4

HCID 7503Benzyl ChlorideHCID 11430Potassium CarbonateHCID 53809767-hydroxy-2-methyl-3-phenyl-4H-chromen-4-oneHCID 5462222Potassium

생성물 1

HCID 907980HCID 907980, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

10 g of 7-hydroxy-2-methyl-isoflavone, 10 g of anhydrous potassium carbonate, 1 g of potassium iddide and 12.5 g of benzyl chloride are boiled in 200 ml of anhydrous acetone for 2 hours with stirring, under a reflux condenser. On subjecting the mixture to steam distillation, the crude product precipitating from a mixture of 100 ml of methanol and 40 ml of acetone, yielding white needle crystalls of 7-benzyloxy-2-methyl-isoflavone, m.p. 139°-141°C.

후처리

  1. distillationto steam distillation
  2. customthe crude product precipitating from a mixture of 100 ml of methanol and 40 ml of acetone

출처 및 근거

ORD 기록
ord-1311fa64aceb45259f3067e9ed19482b
출처 데이터셋
uspto-grants-1976_04
특허 번호
US03949085

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