Hydrochloric Acid → 3,5-Dinitro-4-phenylbenzoic acid

HRID 1605541노트

반응식

HRID 1605541 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([CH:11]=[C:12]([N+:20]([O-:22])=[O:21])[C:13]=1[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:7]([O:9]C)=[O:8])([O-:3])=[O:2].Cl>COCCO.[OH-].[Na+].O>[N+:1]([C:4]1[CH:5]=[C:6]([CH:11]=[C:12]([N+:20]([O-:22])=[O:21])[C:13]=1[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:7]([OH:9])=[O:8])([O-:3])=[O:2]

참가 물질

6

반응물 2

HCID 313Hydrochloric AcidHCID 21546857Methyl 3,5-dinitro-4-phenylbenzoate

생성물 1

HCID 124087663,5-Dinitro-4-phenylbenzoic acid

시약·촉매·용매 3

HCID 962Water용매HCID 80192-Methoxyethanol용매HCID 14798Sodium Hydroxide용매

실험 절차

To a stirred suspension of methyl 3,5-dinitro-4-phenylbenzoate (145 g) in 2-methoxyethanol (1.5 l), 2 N sodium hydroxide (300 ml) is added dropwise during about 30 minutes. After additional stirring for about 15 minutes, the resulting solution is acidified by the dropwise addition of 4 N hydrochloric acid (250 ml), and the mixture is thereafter diluted with water (about 3 l). After cooling, the resulting precipitate is collected by filtration, washed with water and dried. After recrystallization from aqueous ethanol, 3,5-dinitro-4-phenylbenzoic acid is obtained with a melting point of 219°-221° C.

후처리

  1. additionis added dropwise during about 30 minutes
  2. temperatureAfter cooling
  3. filtrationthe resulting precipitate is collected by filtration
  4. washwashed with water
  5. customdried
  6. customAfter recrystallization from aqueous ethanol

출처 및 근거

ORD 기록
ord-4c8168bf01524a988dc6f94f110ccbc7
출처 데이터셋
uspto-grants-1976_04
특허 번호
US03950380

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