Hydrochloric Acid → 5-(3-Methylbutoxy)-2-propylthiophenol

HRID 1606105노트

반응식

HRID 1606105 반응식
CN(C)C(=O)[S:4][C:5]1[CH:10]=[C:9]([O:11][CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15])[CH:8]=[CH:7][C:6]=1[CH2:17][CH2:18][CH3:19].[OH-].[K+].CNC.Cl>O.C(O)COCCO>[CH3:15][CH:14]([CH3:16])[CH2:13][CH2:12][O:11][C:9]1[CH:8]=[CH:7][C:6]([CH2:17][CH2:18][CH3:19])=[C:5]([SH:4])[CH:10]=1

참가 물질

7

반응물 4

HCID 313Hydrochloric AcidHCID 674DimethylamineHCID 14797Potassium HydroxideHCID 21545974S-5-(3-methylbutoxy)-2-propylphenyl N,N-dimethylthiocarbamate

생성물 1

HCID 215459855-(3-Methylbutoxy)-2-propylthiophenol

시약·촉매·용매 2

HCID 962Water용매HCID 8117Diethylene Glycol용매

실험 절차

A solution of 136.1 parts of S-5-(3-methylbutoxy)-2-propylphenyl N,N-dimethylthiocarbamate and 280 parts of potassium hydroxide in 1000 parts of digol was stirred under nitrogen at 120° - 130° for 9 hours, after which no dimethylamine could be detected in the effluent nitrogen. The mixture was cooled, poured into 8000 parts of water and the resulting solution was acidified to pH 1 with hydrochloric acid. The mixture was extracted with ether and the latter was washed with water, dried over magnesium sulphate, filtered and evaporated to dryness to give 95.7 g of the desired product 5-(3-methylbutoxy)-2-propylthiophenol.

후처리

  1. temperatureThe mixture was cooled
  2. extractionThe mixture was extracted with ether
  3. washthe latter was washed with water
  4. dry with materialdried over magnesium sulphate
  5. filtrationfiltered
  6. customevaporated to dryness

출처 및 근거

ORD 기록
ord-b1f54d07f00b402ab11bb08dbc9756b0
출처 데이터셋
uspto-grants-1976_04
특허 번호
US03952013

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