Hydrochloric Acid → Phenolindophenol

HRID 1606694

반응식

HRID 1606694 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.C[C:10]1[C:15](N)=[CH:14][CH:13]=[C:12](C)[C:11]=1[OH:18].Cl>[OH-].[Na+]>[CH:7]1[C:2](=[N:1][C:14]2[CH:13]=[CH:12][C:11]([OH:18])=[CH:10][CH:15]=2)[CH:3]=[CH:4][C:5](=[O:8])[CH:6]=1

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 4034-AminophenolHCID 814773-Amino-2,6-dimethylphenol

생성물 1

HCID 10379Phenolindophenol수율 106.4%

시약·촉매·용매 1

HCID 14798Sodium Hydroxide용매2회

실험 절차

A first solution is prepared by dissolving 0.02 mole (2.18 g) of paraaminophenol in 200 cm3 of a 0.1 N NaOH solution. A second solution is prepared by dissolving 0.01 mole (1.37 g) of 2,6-dimethyl-3-amino phenol also in 100 cm3 of 0.1 N NaOH solution. The two solutions are mixed and air is bubbles for 2 hours in the resulting mixture at ambient temperature. The pH of the reaction mass in then brought to 5 by addition of an aqueous hydrochloric acid solution. The reaction mass is then filtered off to produce 2.12 g of said indophenol which, after recrystallization in a dimethylformamide-water mixture, melts at 248°C.

후처리

  1. customA first solution is prepared
  2. customA second solution is prepared
  3. additionThe two solutions are mixed
  4. customfor 2 hours
  5. customat ambient temperature
  6. filtrationThe reaction mass is then filtered off

출처 및 근거

ORD 기록
ord-86e3dd5d03a94f1388961fe451c137c5
출처 데이터셋
uspto-grants-1976_04
특허 번호
US03953508

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