Sodium → HCID 178444960, 화합물

HRID 1609290

반응식

HRID 1609290 반응식
[NH:1]1[C:5]([CH:6]([O:8][C:9]2[CH:10]=[C:11]([CH:35]=[CH:36][CH:37]=2)[O:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[NH:19][C:20](=[O:34])[C:21]2[CH:26]=[CH:25][C:24]([O:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])=[CH:23][CH:22]=2)[CH3:7])=[N:4][N:3]=[N:2]1.[Na:38]>CCOCC.C(O)C>[Na:38].[NH:4]1[C:5]([CH:6]([O:8][C:9]2[CH:10]=[C:11]([CH:35]=[CH:36][CH:37]=2)[O:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[NH:19][C:20](=[O:34])[C:21]2[CH:22]=[CH:23][C:24]([O:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])=[CH:25][CH:26]=2)[CH3:7])=[N:1][N:2]=[N:3]1

참가 물질

5

반응물 2

HCID 5360545SodiumHCID 178444959HCID 178444959, 화합물

생성물 1

HCID 178444960HCID 178444960, 화합물수율 92.5%

시약·촉매·용매 2

HCID 702Ethanol용매HCID 3283Diethyl Ether용매

실험 절차

In 30 ml of ether was dissolved 2.0 g of N-[2-[3-[1-(1H-tetrazol-5-yl)ethoxy]phenoxy]phenyl]-4-hexyloxybenzamide followed by addition of a solution of 90 mg of sodium in ethanol, and the mixture was concentrated in vacuo to dryness. After addition of isopropyl ether, the resulting foamy solid was pulverized, filtered and dried to give 1.9 g of the sodium salt as a white amorphous powder.

후처리

  1. concentrationthe mixture was concentrated in vacuo to dryness
  2. additionAfter addition of isopropyl ether
  3. filtrationfiltered
  4. customdried

출처 및 근거

ORD 기록
ord-d1a9acbae6d7492d8361972f84ec0462
출처 데이터셋
uspto-grants-1995_03
특허 번호
US05399703

연결된 노트

불러오는 중…