Cyclohexanol → Cyclohexyl 5-amino-4-oxopentanoate--hydrogen chloride (1/1)

반응식

[CH:1]1([OH:7])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Cl.[NH2:9][CH2:10][C:11](=[O:17])[CH2:12][CH2:13][C:14](O)=[O:15].S(Cl)([Cl:20])=O>>[ClH:20].[NH2:9][CH2:10][C:11](=[O:17])[CH2:12][CH2:13][C:14]([O:7][CH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)=[O:15]

참가 물질

반응물 3

HCID 7966Cyclohexanol

HCID 24386Thionyl Chloride

HCID 123608Aminolevulinic Acid Hydrochloride

생성물 1

HCID 22253131Cyclohexyl 5-amino-4-oxopentanoate--hydrogen chloride (1/1)

실험 절차

From cyclohexanol (6.0 ml) and 5-amino-4-oxopentanoic acid hydrochloride (1.0 g; 6.0 mmol) at 80° C. Thionyl chloride was added at room temperature. The reaction was, complete after 3 h. The yield was 1.48 g (99%).

후처리

customat 80° C

출처 및 근거

ORD 기록: ord-8390aec3577147d2b9fbc837827b3adc
출처 데이터셋: uspto-grants-2006_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06992107B1

반응 노트

불러오는 중…