Hydrochloric Acid → 4-(7-Octenyloxy)benzoic acid

HRID 1612582

반응식

HRID 1612582 반응식
Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH:8]=[CH2:9].[OH:10][C:11]1[CH:21]=[CH:20][C:14]([C:15]([O:17]CC)=[O:16])=[CH:13][CH:12]=1.C(=O)([O-])[O-].[K+].[K+].[OH-].[Na+].Cl>C(O)C.O>[CH2:2]([O:10][C:11]1[CH:21]=[CH:20][C:14]([C:15]([OH:17])=[O:16])=[CH:13][CH:12]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH:8]=[CH2:9]

참가 물질

8

반응물 5

HCID 313Hydrochloric AcidHCID 8434EthylparabenHCID 11430Potassium CarbonateHCID 14798Sodium HydroxideHCID 759078-Bromooct-1-ene

생성물 1

HCID 139976794-(7-Octenyloxy)benzoic acid수율 89%

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

9.4 g of 8-bromo-1-octene, 9.0 g of ethyl p-hydroxybenzoate, and 7.6 g of potassium carbonate were refluxed in ethanol for 10 hours. Thereto added was an aqueous solution containing 2.4 g of sodium hydroxide, and then reflux was further continued for 10 hours. After conclusion of the reaction, the reaction solution was diluted with water, and the pH of the solution was lowered to 2 by dropping hydrochloric acid. The generated precipitate was collected, washed sufficiently with water, and dried, to obtain 10.8 g of the objective ether compound. (Yield: 89%)

후처리

  1. additionThereto added
  2. temperaturereflux
  3. customAfter conclusion of the reaction
  4. customThe generated precipitate was collected
  5. washwashed sufficiently with water
  6. customdried
  7. customto obtain 10.8 g of the objective ether compound

출처 및 근거

ORD 기록
ord-488841faf8524eb5b56e415e4aa4a1cf
출처 데이터셋
uspto-grants-1993_03
특허 번호
US05190686

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