N-((1,1-dimethylethoxy)carbonyl)-beta-alanine → 2-{4-(2-(Azetidin-1-yl)-6-({(2-(4-chlorophenyl)-1,3-thiazol-4-yl)methyl}sulfanyl)-3,5-dicyanopyridin-4-yl)phenoxy}ethyl N-(tert-butoxycarbonyl)-beta-alaninate

반응식

[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][C:11]([OH:13])=[O:12])=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl.CN(C)CCCN=[C:21]=[N:22][CH2:23][CH3:24].[Cl:26][C:27]1[CH:32]=[CH:31][C:30]([C:33]2[S:34][CH:35]=[C:36]([CH2:38][S:39][C:40]3[C:45]([C:46]#[N:47])=[C:44]([C:48]4[CH:53]=[CH:52][C:51]([O:54][CH2:55][CH2:56]O)=[CH:50][CH:49]=4)[C:43]([C:58]#[N:59])=[CH:42][N:41]=3)[N:37]=2)=[CH:29][CH:28]=1>CN(C=O)C.ClCCl.CN(C)C1C=CN=CC=1>[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][C:11]([O:13][CH2:56][CH2:55][O:54][C:51]1[CH:52]=[CH:53][C:48]([C:44]2[C:45]([C:46]#[N:47])=[C:40]([S:39][CH2:38][C:36]3[N:37]=[C:33]([C:30]4[CH:29]=[CH:28][C:27]([Cl:26])=[CH:32][CH:31]=4)[S:34][CH:35]=3)[N:41]=[C:42]([N:22]3[CH2:21][CH2:24][CH2:23]3)[C:43]=2[C:58]#[N:59])=[CH:49][CH:50]=1)=[O:12])=[O:7])([CH3:4])([CH3:2])[CH3:3]