Phosphorus oxychloride → HCID 53407931, 화합물

HRID 1622332

반응식

HRID 1622332 반응식
[CH3:1][C:2]1[C:3](=O)[NH:4][CH:5]=[N:6][CH:7]=1.P(Cl)(Cl)([Cl:11])=O>>[ClH:11].[Cl:11][C:3]1[C:2]([CH3:1])=[CH:7][N:6]=[CH:5][N:4]=1

참가 물질

3

반응물 2

HCID 24813Phosphorus oxychlorideHCID 2053244-Pyrimidinol, 5-methyl-

생성물 1

HCID 53407931HCID 53407931, 화합물

반응 조건

온도
90 °C

실험 절차

A mixture of 5-methyl-3H-pyrimidin-4-one (0.60 g, 3.6 mmol) and phosphorous oxychloride (2.0 mL) was heated at 90° C. for 2.5 h. The mixture was evaporated to dryness under reduced pressure and the resultant solid was purified by sublimation under reduced pressure to furnish the title compound as a white solid. This compound was unstable to air and was used immediately in the next step.

후처리

  1. customThe mixture was evaporated to dryness under reduced pressure
  2. customthe resultant solid was purified by sublimation under reduced pressure

출처 및 근거

ORD 기록
ord-5c6992e2e2cc4d99b61018019e5c64be
출처 데이터셋
uspto-grants-2014_07
특허 번호
US08778925B2

연결된 노트

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