Lithium Hydroxide → 3-(2-Chloroethoxy)propanoic acid
반응식
[Cl:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][C:7]([O:9]CC)=[O:8].[OH-].[Li+]>C(O)C>[Cl:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][C:7]([OH:9])=[O:8]참가 물질
4
실험 절차
2.00 g (11.1 mmol) ethyl 3-(2-chloro-ethoxy)-propionate are suspended in 8 ml of ethanol and 4.96 ml (16.6 mmol) of 8% lithium hydroxide solution are added. The mixture is stirred for 4 hours at ambient temperature, then evaporated down i. vac., acidified with 2-molar hydrochloric acid, combined with diethyl ether and dried over sodium sulphate. Then it is filtered off and evaporated down i. vac.
후처리
- customevaporated down i
- dry with materialdried over sodium sulphate
- filtrationThen it is filtered off
- customevaporated down i
출처 및 근거
- ORD 기록
- ord-91e653f6c9934104be09a854ffda7f38
- 출처 데이터셋
- uspto-grants-2014_07
- 특허 번호
- US08791103B2
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