Hydrochloric Acid → Acetophenone

HRID 1649590

반응식

HRID 1649590 반응식
Cl.C[CH:3](N(C)C)[CH:4]([OH:11])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.C(NC1C=CC=CC=1)C>[OH-].[Na+]>[C:4]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)(=[O:11])[CH3:3]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 4374N-MethylephedrineHCID 7670N-Ethylaniline

생성물 1

HCID 7410Acetophenone

시약·촉매·용매 1

HCID 14798Sodium Hydroxide용매

실험 절차

The aqueous layer and the 10% hydrochloric acid washings were joined and the joined solution was mixed with a 10% sodium hydroxide solution (30 ml) to adjust the pH to about 11 and extracted with ethyl acetate (50 ml×3). The extract was washed with a saturated saline solution (50 ml×3), dried and then ethyl acetate was distilled off to obtain a mixture of N-methylephedrine and N-ethylaniline. Yield: 2.4 g (100%). Said two substances can be recovered, separately by distilling the mixture under reduced pressure.

후처리

  1. extractionextracted with ethyl acetate (50 ml×3)
  2. washThe extract was washed with a saturated saline solution (50 ml×3)
  3. customdried
  4. distillationethyl acetate was distilled off
  5. customto obtain
  6. customcan be recovered
  7. distillationseparately by distilling the mixture under reduced pressure

출처 및 근거

ORD 기록
ord-688971b6375e4e3099da4d666833e252
출처 데이터셋
uspto-grants-1983_11
특허 번호
US04418218

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