Formaldehyde → HCID 14751299, 화합물

HRID 1651129노트

반응식

HRID 1651129 반응식
[CH3:1][C:2]([C:5]1[CH:6]=[C:7]([CH:16]=[CH:17][C:18]=1[OH:19])[C:8]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:9])([CH3:4])[CH3:3].Cl.[CH3:21][NH:22][CH3:23].[OH-].[Na+].[CH2:26]=O>C(O)C>[CH3:21][N:22]([CH2:26][C:17]1[CH:16]=[C:7]([CH:6]=[C:5]([C:2]([CH3:1])([CH3:3])[CH3:4])[C:18]=1[OH:19])[C:8]([C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)=[O:9])[CH3:23]

참가 물질

6

반응물 4

HCID 712FormaldehydeHCID 10473Dimethylamine, hydrochlorideHCID 14798Sodium HydroxideHCID 230514754-Benzoyl-2-tert-butylphenol

생성물 1

HCID 14751299HCID 14751299, 화합물수율 68.6%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

3-(1,1-Dimethylethyl)-4-hydroxybenzophenone (2.5 g), 1.71 g of dimethylamine hydrochloride, 0.78 g of sodium hydroxide, and 0.68 g of paraformaldehyde were dissolved in 30 ml of ethanol and the mixture was heated to reflux for 16 hours. The ethanol was then evaporate. Water was added to the residue and the crystals which separated out were filtered and recrystallized from 90% ethanol to give 2.1 g of the desire product, m.p. 129° C.

후처리

  1. temperaturethe mixture was heated
  2. temperatureto reflux for 16 hours
  3. customThe ethanol was then evaporate
  4. additionWater was added to the residue
  5. customthe crystals which separated out
  6. filtrationwere filtered
  7. customrecrystallized from 90% ethanol

출처 및 근거

ORD 기록
ord-5eb76259076143588cb276fb41a5f248
출처 데이터셋
uspto-grants-1990_05
특허 번호
US04927835

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