Hydrochloric Acid → HCID 178418437, 화합물

HRID 1662

반응식

HRID 1662 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([O:11][C@H:12]2[CH2:17][CH2:16][C@H:15]([C:18]3[CH:23]=[CH:22][C:21]([CH2:24][N:25]([CH3:27])[CH3:26])=[CH:20][CH:19]=3)[CH2:14][CH2:13]2)=[O:10])=[CH:4][CH:3]=1.Cl>C(OCC)C.C(O)(C)C>[ClH:1].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([O:11][C@H:12]2[CH2:13][CH2:14][C@H:15]([C:18]3[CH:19]=[CH:20][C:21]([CH2:24][N:25]([CH3:26])[CH3:27])=[CH:22][CH:23]=3)[CH2:16][CH2:17]2)=[O:10])=[CH:4][CH:3]=1

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 178418347HCID 178418347, 화합물

생성물 1

HCID 178418437HCID 178418437, 화합물

시약·촉매·용매 2

HCID 3283Diethyl Ether용매HCID 3776Isopropanol용매

실험 절차

A solution of 0.39 g (0.001 mol) of trans-O-(4-chlorophenylacetyl)-4-(4-dimethylaminomethylphenyl)-cyclohexanol in 10 ml of diethyl ether is combined at ambient temperature, with stirring, with a 1.5 times equimolar amount of hydrogen chloride in isopropanol added dropwise. The precipitate formed is left for 1 hour at ambient temperature, suction filtered, washed repeatedly with diethyl ether and dried. White crystals are obtained, melting point 231°-233° C.

후처리

  1. customis combined at ambient temperature
  2. additionadded dropwise
  3. customThe precipitate formed
  4. filtrationsuction filtered
  5. washwashed repeatedly with diethyl ether
  6. customdried
  7. customWhite crystals are obtained

출처 및 근거

ORD 기록
ord-cf6dff211f2249548afbc224153b66a4
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05726205

연결된 노트

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