Methyl iodide → 2,2,3-Trimethyl-5-methoxy-6,7-dichloro-1-indanone

HRID 1679731노트

반응식

HRID 1679731 반응식
[CH3:1][CH:2]1[CH:10]([CH3:11])[C:9]2[C:4](=[C:5]([Cl:15])[C:6]([Cl:14])=[C:7]([O:12][CH3:13])[CH:8]=2)[C:3]1=[O:16].[H-].[Na+].[CH3:19]I>COCCOC>[CH3:1][C:2]1([CH3:19])[CH:10]([CH3:11])[C:9]2[C:4](=[C:5]([Cl:15])[C:6]([Cl:14])=[C:7]([O:12][CH3:13])[CH:8]=2)[C:3]1=[O:16]

참가 물질

5

반응물 3

HCID 6328Methyl iodideHCID 24758Sodium hydrideHCID 203584412,3-Dimethyl-5-methoxy-6,7-dichloro-1-indanone

생성물 1

HCID 203584512,2,3-Trimethyl-5-methoxy-6,7-dichloro-1-indanone

시약·촉매·용매 1

HCID 80711,2-Dimethoxyethane용매

실험 절차

By following the procedure described in Example 5, Step E, using as the reactants 2,3-dimethyl-5-methoxy-6,7-dichloro-1-indanone (13 g., 0.05 mole), sodium hydride (1.44 g., 0.06 mole), 1,2-dimethoxyethane (500 ml.) and methyl iodide (8 ml.), there is obtained 2,2,3-trimethyl-5-methoxy-6,7-dichloro-1-indanone.

출처 및 근거

ORD 기록
ord-8e6790a3223c42b4a64addf073dfd8af
출처 데이터셋
uspto-grants-1978_03
특허 번호
US04081554

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