Hydrochloric Acid → HCID 12898551, 화합물

HRID 1680254노트

반응식

HRID 1680254 반응식
[F:1][C:2]([F:25])([F:24])[C:3]([C:9]1[CH:21]=[C:20]([CH3:22])[C:12]([O:13][CH2:14][C:15]([O:17]CC)=[O:16])=[C:11]([CH3:23])[CH:10]=1)([OH:8])[C:4]([F:7])([F:6])[F:5].[OH-].[Na+].Cl>>[F:1][C:2]([F:24])([F:25])[C:3]([C:9]1[CH:21]=[C:20]([CH3:22])[C:12]([O:13][CH2:14][C:15]([OH:17])=[O:16])=[C:11]([CH3:23])[CH:10]=1)([OH:8])[C:4]([F:5])([F:7])[F:6]

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 12898550HCID 12898550, 화합물

생성물 1

HCID 12898551HCID 12898551, 화합물

실험 절차

Stir together for 16 hours a mixture of ethyl 2-[4-(hexafluoro-2-hydroxy-2-propyl)-2,6-dimethylphenoxy]acetate (7.1 g=19 mmol) and 125 ml 1.0 N NaOH. Acidify with concentrated HCl and extract with ether. Dry and concentrate the ether. Recrystallize from ether-hexane to obtain, as white crystals, 2-[4-(hexafluoro-2-hydroxy-2-propyl)-2,6-dimethylphenoxy]acetic acid, m.p. 118°-120° C.

후처리

  1. extractionextract with ether
  2. customDry
  3. concentrationconcentrate the ether
  4. customRecrystallize from ether-hexane

출처 및 근거

ORD 기록
ord-a8ef2f71b2b24405b00ace1d6677ff55
출처 데이터셋
uspto-grants-1981_06
특허 번호
US04272550

반응 노트

불러오는 중…