Methylhydrazine → N-methylbenzohydrazide
반응식
[CH3:1][NH:2][NH2:3].[C:4](Cl)(=[O:11])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1>ClCCl>[C:4]([N:2]([CH3:1])[NH2:3])(=[O:11])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1참가 물질
4
실험 절차
Methylhydrazine (0.212 ml, 4.0 mmol) was dissolved in dichloromethane (10 ml) and was treated dropwise with benzoylchloride (0.232 ml, 2.0 mmol) in dichloromethane (5 ml). After stirring for 0.5h the solution was evaporated to dryness. The residue was partitioned between water and ethyl acetate. The organic phase was dried and evaporated under reduced pressure to give the title compound (0.20 g, 65%); δH (CDCl3) 3.13 (3H, s), 4.5 (2H, brs), and 7.30 (5H, s).
후처리
- customwas evaporated to dryness
- customThe residue was partitioned between water and ethyl acetate
- customThe organic phase was dried
- customevaporated under reduced pressure
출처 및 근거
- ORD 기록
- ord-64901f962b6946c588844917b5af40ea
- 출처 데이터셋
- uspto-grants-1996_04
- 특허 번호
- US05504076
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