Hydroxylamine → Carbamic acid, hydroxy-, butyl ester

HRID 1721485노트

반응식

HRID 1721485 반응식
S([O-])([O-])(=O)=O.[NH2:6][OH:7].Cl[C:9]([O:11][CH2:12][CH2:13][CH2:14][CH3:15])=[O:10].[OH-].[Na+]>>[OH:7][NH:6][C:9](=[O:10])[O:11][CH2:12][CH2:13][CH2:14][CH3:15]

참가 물질

5

반응물 4

HCID 787HydroxylamineHCID 1117Sulfate IonHCID 14798Sodium HydroxideHCID 61140Butyl chloroformate

생성물 1

HCID 164691Carbamic acid, hydroxy-, butyl ester

실험 절차

With respect to butyl N,O-dimethylcarbamate, a process disclosed in the specification of West German Patent Application Laid-open No. 3,245,503 is known. This process comprises reacting sulfate of hydroxylamine as a starting material with butyl chloroformate in the presence of sodium hydroxide, extracting the reaction product with dichloromethane, drying the extract, distilling the solvent away from the dried extract to obtain butyl hydroxycarbamate and dimethylating this product using dimethyl sulfate and a sodium hydroxide solution to obtain ethyl N,O-dimethylhydroxycarbamate in the total yield of 65%.

후처리

  1. extractionextracting the reaction product with dichloromethane
  2. customdrying the extract
  3. distillationdistilling the solvent away from the dried
  4. extractionextract

출처 및 근거

ORD 기록
ord-f9be280d60b6463ebc14cd7f5a4e6742
출처 데이터셋
uspto-grants-1996_04
특허 번호
US05510511

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