2-Propanethiol → Ethyl (isopropylthio)acetate
반응식
[Na].[SH:2][CH:3]([CH3:5])[CH3:4].Br[CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9]>C(O)C>[CH3:4][CH:3]([S:2][CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH3:5]참가 물질
5
실험 절차
To sodium (4.2 g, 0.18 mol) in ethanol (100 mL) was added 2mercaptopropane (20 mL), 0.21 mol) followed by ethyl bromoacetate (10 mL, 0.090 mol). The mixture was stirred for 12 hours, concentrated, partitioned between ether and water and washed with water. The organic phase was dried over MgSO4, evaporated and distilled to afford the desired product. B.P. 58°-62° C. (1 mm).
후처리
- concentrationconcentrated
- custompartitioned between ether and water
- washwashed with water
- dry with materialThe organic phase was dried over MgSO4
- customevaporated
- distillationdistilled
출처 및 근거
- ORD 기록
- ord-621540d05d9e4f92bffb5ed2715a18aa
- 출처 데이터셋
- uspto-grants-1989_08
- 특허 번호
- US04857507
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