Chloroform → HCID 54205117, 화합물

HRID 1730307노트

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HRID 1730307 반응식
[C:1]1([N:7]2[C:11](=[NH:12])[C:10](=[O:13])[N:9]([CH3:14])[C:8]2=[O:15])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[O:16]=[CH:17][C:18]([Cl:21])([Cl:20])[Cl:19].C(Cl)(Cl)[Cl:23]>>[C:1]1([N:7]2[C:11](=[N:12][C:17]([OH:16])([Cl:23])[C:18]([Cl:21])([Cl:20])[Cl:19])[C:10](=[O:13])[N:9]([CH3:14])[C:8]2=[O:15])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 3

HCID 6212ChloroformHCID 6407ChloralHCID 214974605-Imino-3-methyl-1-phenylimidazolidine-2,4-dione

생성물 1

HCID 54205117HCID 54205117, 화합물

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온도
20 °C

실험 절차

1-phenyl-3-methyl-5-iminoimidazolidine-2,4-dione (15.0 g -- 0.074 mol) was slurried in 40 ml chloroform. Chloral (21.8 g -- 0.148 mol) was added directly to the slurry. Exothermicity raised the temperature 20° C.The reaction mixture was momentarily homogeneous before an abundance of product precipitated. An additional 100 ml of chloroform was added at thispoint. After 0.5 hour the mixture was filtered. The filter cake was washed with chloroform and dried. The product melted at 130°-133° C.

후처리

  1. customprecipitated
  2. additionAn additional 100 ml of chloroform was added at thispoint
  3. filtrationAfter 0.5 hour the mixture was filtered
  4. washThe filter cake was washed with chloroform
  5. customdried

출처 및 근거

ORD 기록
ord-219a48721f5f443cb6d2e9a182aef157
출처 데이터셋
uspto-grants-1976_11
특허 번호
US03992402

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