Methanesulfonic Acid → 5-Methyl-N-{5-methyl-6-[4-(morpholin-4-yl)cyclohex-1-en-1-yl]pyridin-3-yl}-1-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazole-4-carboxamide mesylate

반응식

[F:1][C:2]([F:19])([F:18])[C:3]1[CH:4]=[CH:5][C:6]([N:9]2[C:13]([CH3:14])=[C:12]([C:15]([NH2:17])=[O:16])[CH:11]=[N:10]2)=[N:7][CH:8]=1.[N:20]1([CH:26]2[CH2:31][CH2:30][C:29]([C:32]3[C:37]([CH3:38])=[CH:36][C:35](Br)=[CH:34][N:33]=3)=[CH:28][CH2:27]2)[CH2:25][CH2:24][O:23][CH2:22][CH2:21]1.C(=O)([O-])[O-].[Cs+].[Cs+].[CH3:46][S:47]([OH:50])(=[O:49])=[O:48]>O1CCOCC1.C(Cl)(Cl)Cl.C([O-])(=O)C.[Pd+2].C([O-])(=O)C.C1(P(C2C=CC=CC=2)C2C3OC4C(=CC=CC=4P(C4C=CC=CC=4)C4C=CC=CC=4)C(C)(C)C=3C=CC=2)C=CC=CC=1>[S:47]([OH:50])(=[O:49])(=[O:48])[CH3:46].[CH3:14][C:13]1[N:9]([C:6]2[CH:5]=[CH:4][C:3]([C:2]([F:1])([F:18])[F:19])=[CH:8][N:7]=2)[N:10]=[CH:11][C:12]=1[C:15]([NH:17][C:35]1[CH:34]=[N:33][C:32]([C:29]2[CH2:30][CH2:31][CH:26]([N:20]3[CH2:21][CH2:22][O:23][CH2:24][CH2:25]3)[CH2:27][CH:28]=2)=[C:37]([CH3:38])[CH:36]=1)=[O:16]